Tobacco and Smoking Cessation

Biography

Biography: Baurzhan Zhussupov

Abstract

a. Statement of the Problem

To establish whether smokers who pass from cigarettes to IQOS, "heat-not-burn" tobacco product, reduce the risk for health, KAPM is conducting a 5-year prospective cohort study among IQOS and traditional cigarette users. After baseline information was collected, we compare two cohorts on baseline health status measurements namely spirometry and metabolic syndrome.

b. Methodology & Theoretical Orientation

Two cohorts of participants were recruited: men and women age 40 – 59 residing in Almaty City of Kazakhstan: 800 smokers of conventional cigarettes and 400 users of IQOS matched by gender, age, education and pack-year smoking history. The baseline clinical assessments included spirometry, metabolic syndrome and anthropometry. FEV1/FVC ratio less than 0.7 was used to define COPD. We utilized IDF clinical criteria for the metabolic syndrome. Logistic regression is used for estimating the adjusted prevalence odds ratio (aPOR). Age, gender, pack-year, education, current tobacco product use status were used as independent variables.

c. Findings

COPD was more prevalent in males than in females (4.5% vs 1.3%, aPOR=3.88, 95%CI, 1.59-9.51), among 50-59 than among 40-49-year-old (4.7% vs 1.3%, aPOR=4.39, 95%CI, 1.94-9.97), without college degree than with college degree (7.0% vs 2.2%, aPOR=3.57, 95%CI, 1.66-7.70). Metabolic syndrome was more common in males than in females (40.4% vs 26.8%, aPOR=1.54, 95%CI, 1.18-2.02), among 50-59 than among 40-49-year-old (38.0% vs 29.7%, aPOR=1.36, 95%CI, 1.06-1.75), having 20+ pack-year than 10-19.9 pack-year smoking history (40.7% vs 25.0%, aPOR=1.76, 95%CI, 1.33-2.33).

d. Conclusion & Significance

Older age and male gender were positively associated with both COPD and metabolic syndrome in persons with smoking history. No statistically significant differences in COPD and metabolic syndrome were observed between conventional cigarette and IQOS users at the baseline.